Reductive Stress and Mitochondrial Dysfunction The - Hidden Link in Chronic Disease
Stress is a big factor when things go wrong. I've been taking Niacinamide for decades. To be honest, I never knew what it really did.
DIVINE INTERVENION steps in when I don't know what causes good events to happen.
It only applies to positive things. Negative things are usually caused by my stupidity!
Story at-a-glance
- My paper, published in Free Radical Biology and Medicine, reveals how reductive stress is an early, hidden breakdown in mitochondrial function that leads to chronic fatigue, brain fog, and metabolic diseases, even if your blood tests look normal
- Overeating healthy or unhealthy fats and carbs overloads your mitochondria with excess NADH and FADH2, jamming energy production and triggering cell damage from within
- High-fat, low-carb diets that include vegetable oils rich in linoleic acid (LA) quietly worsen mitochondrial stress and reverse electron flow, increasing oxidative byproducts
- Reductive stress disrupts your body's natural antioxidant defenses, draining NADPH and stalling key enzymes that protect your cells from damage
- Targeted steps like eliminating vegetable oils and endocrine disruptors, taking low-dose niacinamide, testing redox ratios, and moving your body gently help restore energy production and metabolic flexibility
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